REM Rebound Effect

Sleep is a state consisting of several different stages of reversible disconnection from the environment with accompanying reduced consciousness, atonia, and metabolic changes. These stages are primarily divided into rapid-eye-movement (REM) sleep, which is characterized by classic ocular saccadic movement and fast-wave EEG patterns reminiscent of wakefulness, and non-rapid-eye movement (NREM) which can be subdivided further into three stages each distinguished by distinct EEG wave patterns. Normally an individual will progress through a predictable cycle of stages beginning with wakefulness, then through each stage of NREM sleep before quickly reversing through the stages to enter REM sleep. The maintenance of appropriate sleep architecture appears to play an important role in promoting physiological and mental health. Such health benefits may include modulating memory, emotion, and cognitive integration of stressors and mechanisms are in place to restore sleep homeostasis if sleep is disrupted. One of these mechanisms is REM rebound, which refers to the compensatory increase of the frequency, depth, and intensity of rapid-eye-movement (REM) sleep following sleep deprivation or significant stressors. Several experimental studies utilizing EEG and hormonal measurements have illustrated that human and animal participants who experience sleep deprivation or significant stressors will experience increased frequency and intensity of REM sleep to compensate for said deprivation

Using the EBUS Scope in the Esophagus

This chapter aims at introducing the interested Pulmonologist/Interventional Pulmonologist to the esophageal ultrasound. In this chapter, we give short descriptions of some technical aspects of the endobronchial ultrasound (EBUS) scope and explain in detail why we believe the EBUS scope is well suited to be an esophageal scope in the hands of the trained pulmonologist. The chapter then explains indications and benefits of this procedure that we consider central to the practice of chest physicians. We also describe in steps how to reach each lymph node station using the EBUS scope as a EUS scope (EUS-B) from our own experience. Procedurerelated complications and contraindications are also described

EUS-B for the Interventional Pulmonologist Using the EBUS Scope in the Esophagus

This chapter aims at introducing the interested Pulmonologist/Interventional Pulmonologist to the esophageal ultrasound. In this chapter, we give short descriptions of some technical aspects of the endobronchial ultrasound (EBUS) scope and explain in detail why we believe the EBUS scope is well suited to be an esophageal scope in the hands of the trained pulmonologist. The chapter then explains indications and benefits of this procedure that we consider central to the practice of chest physicians. We also describe in steps how to reach each lymph node station using the EBUS scope as a EUS scope (EUS-B) from our own experience. Procedure-related complications and contraindications are also described

Study of vibrational spectra of polycyclic aromatic hydrocarbons with phenyl side group

Computational study of polycyclic aromatic hydrocarbons (PAHs) with phenyl side group substituted at different positions is reported. The infrared spectral variations due to the position of phenyl substitution, ionization state and the size of the molecules are discussed and possible contribution of phenyl-PAHs to the mid-infrared emission features from astrophysical objects is analyzed. Structurally phenyl group substitution at 2nd position gives more stable species compared to substitution at other positions. Phenyl-PAHs exhibit new aromatic bands near 695 and 741 cm$^{-1}$ (14.4 and 13.5 $\mu$m), due to contribution from quintet C-H wag, that compare well with minor features at 14.2 and 13.5 $\mu$m observed in several astrophysical objects. Just as in plain PAHs, the C-C stretch vibrational modes ($\sim$1600 cm$^{-1}$) have negligible intensity in neutrals, but the cations of all phenyl-PAHs exhibit significantly strong phenyl group C-C stretch peak close to class B type 6.2 $\mu$m astrophysical band. In 2-phenylpyrene, it is the neutral molecule that exhibits this strong feature in the 6.2 $\mu$m range along with other features that match with sub-features at 6.66 and 6.9 $\mu$m, observed in astronomical spectra of some late type objects. The substitution of phenyl side group at solo position shifts the C-C stretch mode of parent PAH close to the region of 6.2 $\mu$m astrophysical band. The results indicate possibility of phenyl-PAHs in space and the bottom-up formation of medium sized compact PAHs with phenyl side group in carbon rich cool circumstellar shells. Phenyl-PAHs need to be considered in modelling mid-infrared emission spectra of various astrophysical objects.Comment: 45 papges including 15 Figures and 3 Table